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News covering selected sessions related to migraine from 2008 medical conferences.
Annual Meeting of the American Academy of Neurology Chicago, IL April 15-18, 2008
 
 
  Migraine Education Reduces Costs to Employers
 
  Similarities Seen in New Daily Persistent Headache and Transformed Migraine
 
Migraine Frequency Tied to Cardiovascular Risk
 
  Transformed Migraine Imposes Substantial Economic Burden
 
  Survey Provides Insight to Frequency of Migraine and
Probably Migraine
 
  Migraine Parameters Improve after Obesity Surgery
 
  Pulsality Index Shows promise for Assessing Intracranial Pressure
 
  Survey Reveals Spotty Patient Knowledge about Headache
 
  Data Strengthen Link between Patent Foramen Ovale, Migraine
 
  Progressive Balance Disorder Seen in patients with Migraine
 
  Basilar Artery Flow Patterns Distinquish Migraine Subtypes
 
  Three-question screening tool identifies patients with Migraine
 
  Transformed Migraine and New Daily Headache Have Similar Symptoms
 
  Migraine Onset and Progression Have Multiple Variations
 
  Mutation Quadruples Stroke Risk in Patients who have Migraine with Aura
 
  Oral Contraceptives Linked to Perimenstrual Migraine
 
  Migraine with Acute Confusion May Be Early Clue to
CADASIL
 
  Lachance First Clinical Data Released on Outbreak of Immune Polyradiculoneuropathy in Pork Processors
 
  Robert One of First Prevalence Studies Finds More Mild Cognitive Impairment in Men
 
  Excessively High, Low HbA1c Levels Carry Elevated Dementia Risk
 
Alzheimer’s Onset Sooner in Heavy Drinkers, Smokers
 
Longer Survival in Alzheimer’s Patients Who Took Vitamin E
 
High Midlife Cholesterol Increases Risk of Alzheimer’s and Dementia
 
Anticholinergic Drugs, Cognitive Decline Linked in Rush Religious Order Study
 
  Treatment Failure has Many Causes, Most of Which can be Corrected
 
  Issues and Challenges Increase in Older Headache Patients
 
  Medication Overuse Headache: New Insights into an Old Problem
 
Migraines Linked to Sleep Disturbances in Children
 
  Migraine Education Reduces Costs to Employers  
BY DON SCHRADER
Contributing Writer
CHICAGO (ECCC)—Educating employees with migraine about their condition may help reduce absenteeism, loss of productivity, and healthcare costs, data from a pilot program suggest.
            Six months after completion of an Internet-based migraine education program, employees at three different work sites had significantly fewer lost work days and lost work hours compared with the three months before the program, reported Matthew J. Page, a health policy analyst for United BioSource Corp. in Bethesda, Md., on April 17 at the annual meeting of the American Academy of Neurology. Page pointed out that although direct costs for migraine care actually increased, they were offset by large reductions in indirect costs.
            “Recognizing the limitations of self-reported recall and the low participation in the follow-up survey, these findings suggest that an educational program for employees can help reduce employer costs associated with migraine and other headache disorders,” said Page. “We observed improvement in various factors that contribute to direct and indirect costs, but the decrease in indirect costs was especially striking.”
            A recent study indicated that the direct cost burden of migraine in the United States surpasses $11 billion annually (Headache. 2008;48:553-563). The estimated indirect costs of migraine approach $12 billion a year (J Occup Environ Med. 2007:49:368-374). Presenteeism (work hours affected by headache and loss of productivity) accounts for 90% of the indirect costs of headache (J Occup Environ Med. 2004;46:398-412).
            Whether an employer-provided educational program could reduce migraine-related costs and productivity loss had not been carefully examined.
Page and his colleagues invited employees from three U.S. worksites to visit a company-specific Web site that briefly described the study and included a six-question migraine-screening instrument that employees could choose to complete. Respondents who answered “yes” to the first question (diagnosis) and to four of the five screening questions were invited to participate in the study.
            Study participants completed a survey that elicited information about migraine frequency and severity. They also answered questions about use of healthcare resources.
            At regular intervals, participants received three emails containing educational materials. They also received six migraine-related newsletters at 2-week intervals.
            Six months after receiving the last email of educational materials, study participants completed a follow-up survey. The baseline and follow-up surveys had a 3-month recall period. Investigators estimated costs from employees’ responses to the surveys.
            For the three worksites combined, 1,463 completed the online screening instrument, and 1,152 qualified to participate in the study. Two thirds of the qualifying respondents had both a migraine diagnosis and positive responses to the screening instrument. Page reported that 917 of the qualifiers completed the baseline survey. However, only 247 of the 917 (27%) completed the follow-up survey, greatly reducing the generalizability of the study findings.
            Both migraine frequency and severity decreased significantly following the educational intervention (P=0.0001, P<0.0001). Use of medications and alternative therapies did not change during the study. Physician office visits decreased significantly (P=0.0374), but visits to emergency rooms increased, though not significantly.
            Lost work days due to migraine decreased significantly from 800 per 1,000 persons in the 3 months before the educational program to 600 per 1,000 in the first 3 months after completion of the program (P=0.0053). The proportion of participants who missed at least 1 day of work because of migraine decreased from 41% to 29%. The number of hours affected by headache remained stable, but self-assessed productivity increased significantly (P=0.0001).
            Estimated direct costs increased from $105,220 per 1,000 migraineurs to $169,780 per 1,000. The increase was driven by increased expenditures for emergency room visits and hospitalizations. Costs associated with physician visits declined.
            Indirect costs decreased from $403,250 per 1,000 migraineurs in the 3 months before baseline to $264,160 per 1,000 at follow-up (P<0.0001). Both absenteeism and presenteeism decreased substantially.
            Total costs (direct and indirect combined) decreased from $508,470 per 1,000 migraineurs to $433,940 per 1,000 (P<0.0001).
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