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| This news site is not sanctioned by, nor part of, the Diamond Headache Foundation, The American Academy of Neurology OR The American Headache Society. |
| News covering selected sessions related to migraine from 2008 medical conferences. |
| Annual Meeting of the American Academy of Neurology |
Chicago, IL April 15-18, 2008 |
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Transformed Migraine and New Daily
Headache Have Similar Symptoms |
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BY DON SCHRADER
Contributing Writer |
CHICAGO
(ECCC)— Similarities in the type and frequency of
symptoms suggest that new daily persistent headache and
transformed migraine have a similar underlying pathophysiology,
investigators reported on April 16 at the annual meeting of the
American Academy of Neurology.
Patients with either type of headache reported similar rates of
phonophobia, nausea, vomiting, and Visual Aura Rating Scale
(VARS) scores >5, reported William L. Cohen, a medical student
at Thomas Jefferson University in Philadelphia. Neither the
location nor the quality of pain associated with headache
differed between patients with the two types of headache.
Rapid onset is a distinguishing feature of new daily persistent
headache, whereas transformed migraine evolves from episodic
headache. Whether the two types of headache are
pathophysiologically distinct remains an unresolved issue.
In the current study, investigators evaluated 50 patients with
new daily persistent headache and 50 age- and gender-matched
patients with transformed migraine. All the patients were
assessed by investigators who were blinded to the patients’
diagnoses and who used Silberstein-Lipton criteria. The study
population consisted of 36 female pairs and 14 male pairs. They
did not differ with respect to age (mean of 37), body mass index
(26.76 for new daily persistent headache vs. 27.29 for
transformed migraine), or history of head injury (36% vs. 32%).
Patients with new daily persistent headache were significantly
less likely to be photophobic (50% vs. 90%, P<0.001) and
osmophobic (36% vs. 64% P=0.009) but more likely to have a
history of seizures (14% vs. 2%, P=0.027) than patients with
transformed migraine. The two groups of patients reported
similar rates of phonophobia (64% vs. 72%), nausea (50% vs.
62%), and vomiting (14% vs. 26%), and 20% of each group had VARS
>5. |
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